Wearable skin patch that continuously monitors temperature and predicts fever onset 2 hours in advance.

A medical device startup looking to create a continuous fever monitoring patch for parents to monitor children's temperature during illness.
Developing a disposable, skin-mountable patch that maintains medical-grade temperature accuracy (±0.1°C) while being thin enough to be comfortable under clothing.
The patch uses the Nordic nRF52840 with a MAX30208 clinical-grade digital temperature sensor (±0.05°C accuracy). A 2-layer flexible PCB is laminated into a 1.5mm-thick silicone patch. A CR2032 battery provides 5 days of continuous monitoring.
The firmware on Zephyr RTOS samples temperature at 1Hz, applies a median filter to remove motion artifacts, and stores a 24-hour rolling history. A lightweight gradient-boosting model on the MCU analyzes the rate of temperature change and circadian pattern deviation to predict fever onset (temperature >=38°C) up to 2 hours in advance. Alerts are sent via BLE to the parent's smartphone.
±0.05°C accuracy validated against rectal thermometer (ISO 80601-56). Fever prediction AUC of 0.94 in pediatric trials. 48-hour earlier fever detection vs. spot checks.
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